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51.
In order to analyze potential social risks, and achieve smooth implementation of investment activities in the China–Pakistan economic corridor (CPEC), we attempt to establish social impact and risk indicators. Both the impacts on the projects and the impacts of the projects are used to develop risk indicators in accordance with the literature review, reality and international standard principles. Using an analytic hierarchy process (AHP) and average value to analyze questionnaires of both Chinese and Pakistani respondents, we identify the importance of various risk indicators. The primary social risks of the western high mountain region include tribal obstacles and religious extremism. The social risks to the southeast coastal plains include preserving the historical and cultural heritage of the area and international protection of national parks. The social risks in north Kashmir include disputes, extremist threats, religious and cultural differences, and the protection of natural reserves. The social risks of the Xinjiang region primarily involve social issues faced by ethnic minorities and environmental pressures.  相似文献   
52.
This work reports data on the occurrence of nine mycotoxins and two food processing contaminants – acrylamide and furan – in a total of 100 beers produced in Latvia. Mycotoxins were detected by high-performance liquid chromatography (HPLC) coupled with time-of-flight mass spectrometry, acrylamide by HPLC coupled with quadrupole-Orbitrap mass spectrometry, and furan by headspace gas chromatography-mass spectrometry. The most frequently occurring mycotoxins were HT-2 and deoxynivalenol (DON), which were detected in 52% and 51% of the analysed samples. The highest content was observed for DON, reaching the maximum of 248 µg kg?1. Furan was ubiquitous, and 74% of the samples contained acrylamide. In terms of the estimated exposure, the biggest potential risk was identified for HT-2 representing more than 11% of tolerable weekly intake. The margin of exposure approach indicated the exposure to furan through beer as significant, this parameter being close to the critical limit.  相似文献   
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54.
A quality-by-design approach was adopted to develop telmisartan potassium (TP) tablets, which were bioequivalent with the commercially available Micardis® (telmisartan free base) tablets. The dissolution pattern and impurity profile of TP tablets differed from those of Micardis® tablets because telmisartan free base is poorly soluble in water. After identifying the quality target product profile and critical quality attributes (CQAs), drug dissolution, and impurities were predicted to be risky CQAs. To determine the exact range and cause of risks, we used the risk assessment (RA) tools, preliminary hazard analysis and failure mode and effect analysis to determine the parameters affecting drug dissolution, impurities, and formulation. The range of the design space was optimized using the face-centered central composite design among the design of experiment (DOE) methods. The binder, disintegrant, and kneading time in the wet granulation were identified as X values affecting Y values (disintegration, hardness, friability, dissolution, and impurities). After determining the design space with the desired Y values, the TP tablets were formulated and their dissolution pattern was compared with that of the reference tablet. The selected TP tablet formulated using design space showed a similar dissolution to that of Micardis® tablets at pH 7.5. The QbD approach TP tablet was bioequivalent to Micardis® tablets in beagle dogs.  相似文献   
55.
High reliability and security have become the hallmarks of complex electromechanical systems. Owing to the difficulties in fault data collection, ambiguity and uncertainty have been inevitably associated with complex electromechanical systems. Thus, the ability to perform reliability evaluation using scarce fault data is of immense significance to these machines and is the focus of this study. A similarity based cloud model is proposed to evaluate the running state of complex electromechanical systems. By combining objective and subjective factors, the reliability of complex electromechanical systems is evaluated by calculating the similarity between the cloud models of actual and standardised states. Next, the inverter of an offshore wind turbine is used to verify the accuracy and effectiveness of the proposed approach. The cloud model based framework for reliability evaluation inherits the preponderance of the uncertainty problem, overcomes the drawbacks of the current reliability approaches, and provides a theoretical basis, as well as a practical approach for the maintenance and repair of complex electromechanical systems with missing fault data. Additionally, it also provides a new methodology for solving the uncertainty problems caused by paucity of data.  相似文献   
56.
This paper proposes an approach to improve the performance of no-reference video quality assessment for sports videos with dynamic motion scenes using an efficient spatiotemporal model. In the proposed method, we divide the video sequences into video blocks and apply a 3D shearlet transform that can efficiently extract primary spatiotemporal features to capture dynamic natural motion scene statistics from the incoming video blocks. The concatenation of a deep residual bidirectional gated recurrent neural network and logistic regression is used to learn the spatiotemporal correlation more robustly and predict the perceptual quality score. In addition, conditional video block-wise constraints are incorporated into the objective function to improve quality estimation performance for the entire video. The experimental results show that the proposed method extracts spatiotemporal motion information more effectively and predicts the video quality with higher accuracy than the conventional no-reference video quality assessment methods.  相似文献   
57.
58.
Hydrogen production by biogas conversion represent a promising solution for reduction of fossil CO2 emissions. In this work, a detailed techno-economic analysis was performed for decarbonized hydrogen production based on biogas conversion using calcium and chemical looping cycles. All evaluated concepts generate 100,000 Nm3/h high purity hydrogen. As reference cases, the biogas steam reforming design without decarbonization and with CO2 capture by gas-liquid chemical absorption were also considered. The results show that iron-based chemical looping design has higher energy efficiency compared with the gas-liquid absorption case by 2.3 net percentage points as well as a superior carbon capture rate (99% vs. 65%). The calcium looping case shows a lower efficiency than chemical scrubbing, with about 2.5 net percentage points, but the carbon capture rate is higher (95% vs. 65%). The hydrogen production cost increases with decarbonization, the calcium looping shows the most favourable situation (37.14 €/MWh) compared to the non-capture steam reforming case (33 €/MWh) and MDEA and iron looping cases (about 42 €/MWh). The calcium looping case has the lowest CO2 avoidance cost (10 €/t) followed by iron looping (20 €/t) and MDEA (31 €/t) cases.  相似文献   
59.
为验证深圳抽水蓄能电厂球阀具备动水关闭能力且不会产生有害振动进行了球阀动水关闭试验,获得不同负荷下球阀动水关闭实测各项动应力值及振动位移值。试验数据表明深蓄电厂球阀在不关闭导叶情况下能可靠关闭阻断上游来水,验证了在100%负荷动水关闭球阀最不利工况下,球阀混凝土支墩结构强度满足设计要求,球阀体系的振动位移是安全的,且对设备未产生有害变形及损坏。  相似文献   
60.
The increased reliance on natural gas for heating worldwide makes the search for carbon-free alternatives imperative, especially if international decarbonisation targets are to be met. Hydrogen does not release carbon dioxide (CO2) at the point of use which makes it an appealing candidate to decarbonise domestic heating. Hydrogen can be produced from either 1) the electrolysis of water with no associated carbon emissions, or 2) from methane reformation (using steam) which produces CO2, but which is easily captured and storable during production. Hydrogen could be transported to the end-user via gas distribution networks similar to, and adapted from, those in use today. This would reduce both installation costs and end-user disruption. However, before hydrogen can provide domestic heat, it is necessary to assess the ‘risk’ associated with its distribution in direct comparison to natural gas. Here we develop a comprehensive and multi-faceted quantitative risk assessment tool to assess the difference in ‘risk’ between current natural gas distribution networks, and the potential conversion to a hydrogen based system. The approach uses novel experimental and modelling work, scientific literature, and findings from historic large scale testing programmes. As a case study, the risk assessment tool is applied to the newly proposed H100 demonstration (100% hydrogen network) project. The assessment includes the comparative risk of gas releases both upstream and downstream of the domestic gas meter. This research finds that the risk associated with the proposed H100 network (based on its current design) is lower than that of the existing natural gas network by a factor 0.88.  相似文献   
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